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  2. Drug Derivative
  3. NA0359

NA0359 is a derivative of SF2370 (HY-N6732). NA0359 inhibits the actin-myosin-ATP interaction in native smooth muscle actomyosin and myosin light chain phosphorylation.

For research use only. We do not sell to patients.

NA0359

NA0359 Chemical Structure

CAS No. : 134931-91-2

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Description

NA0359 is a derivative of SF2370 (HY-N6732). NA0359 inhibits the actin-myosin-ATP interaction in native smooth muscle actomyosin and myosin light chain phosphorylation[1].

In Vitro

NA0359 inhibits both the actin-myosin-ATP interaction and myosin light chain phosphorylation in chicken gizzard smooth muscle native actomyosin, with its inhibitory activity on the interaction being comparable to or less potent than its activity on phosphorylation[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

480.56

Formula

C29H28N4O3

CAS No.
SMILES

O=C1NCC2=C(C3=C(N4[C@]5(C)OC6C[C@]5(CNCCC)O)C=CC=C3)C4=C7N6C8=CC=CC=C8C7=C21

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
NA0359
Cat. No.:
HY-165391
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