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Cat. No.: HY-109153

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Nerindocianine

Nerindocianine is a fluorescent diagnostic contrast agent. Nerindocianine is highly hydrophilic and is primarily metabolized by the kidneys, allowing for a non-invasive intraoperative ureteral imaging.

For research use only. We do not sell to patients.

CAS No.: 748120-01-6
Formula: C₄₄H₅₂N₂O₁₆S₅
Molecular Weight:1025.21

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (275 KB)

Nerindocianine Chemical Structure

CAS No.: 748120-01-6

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vivo
- Clinical Trial
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vivo

Nerindocianine (0.15 mg/kg; i.v.) shows a satisfactory visualization^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Female pigs^[1]
Dosage:

0.15 mg/kg
Administration:

I.v.
Result:

Showed a satisfactory visualization.

Clinical Trial

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991	Plexxikon\|		2011-05	PHASE1

Chemical Information

CAS No. 748120-01-6
Molecular Weight 1025.21
Formula C₄₄H₅₂N₂O₁₆S₅
SMILES

O=S(CCCC[N+]1=C(/C=C/C2=C(OC3=CC=C(S(=O)(O)=O)C=C3)/C(CCC2)=C/C=C4N(CCCCS(=O)(O)=O)C5=C(C=C(S(=O)(O)=O)C=C5)C/4(C)C)C(C)(C)C6=C1C=CC(S(=O)(O)=O)=C6)([O-])=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (275 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Barberio M, et al. Intraoperative ureter identification with a novel fluorescent catheter. Sci Rep. 2021;11(1):4501. Published 2021 Feb 24. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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