Neritaloside
Based on 1 Customer Validation
Neritaloside could be isolated from nerium oleander. Neritaloside has central nervous system (CNS) depressant effect[2.
For research use only. We do not sell to patients.
- Purity: 97%
- CAS No.: 465-13-4
- Formula: C32H48O10
- Molecular Weight:592.72
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Neritaloside (human tumor cell lines) has antitumor activity with mean IC50 value and mean IC70 value of 0.120 μM and 0.252 μM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Mice of NMRI strain (18-22 g) [2
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Dosage:25 mg/kg
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Administration:Intraperitoneal injection; for 6 hours
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Result:Showed sedation in mice at 25 mg/kg dose.
Chemical Information
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CAS No. 465-13-4
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Appearance Solid
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Molecular Weight 592.72
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Formula C32H48O10
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Color White to off-white
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SMILES
C[C@]([C@](C(CO1)=CC1=O)([H])[C@H]2OC(C)=O)(CC[C@@]3([H])[C@@]4([H])CC[C@@](C5)([H])[C@@]3(CC[C@@H]5O[C@H](O[C@@H]6C)[C@@H]([C@H]([C@H]6O)OC)O)C)[C@@]4(C2)O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Rashan LJ, et, al. Characterization of the anticancer properties of monoglycosidic cardenolides isolated from Nerium oleander and Streptocaulon tomentosum. J Ethnopharmacol. 2011 Apr 12;134(3):781-8. [Content Brief]
[2]. Begum S, et, al. Bio-active cardenolides from the leaves of Nerium oleander. Phytochemistry. 1999 Feb;50(3):435-8. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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