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Art. -Nr.: HY-P9968A

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Nimotuzumab (powder)

Name: Nimotuzumab (powder)
Brand: MedChemExpress
SKU: HY-P9968A
Availability: PreOrder

1 Cited Publications

Kundenbewertung

Based on 1 publication(s) in Google Scholar

Nimotuzumab (powder) is a humanized IgG1 monoclonal antibody targeting EGFR with a K_D value of 0.21 nM. Nimotuzumab (powder) is directed against the extracellular domain of the EGFR blocking the binding to its ligands. Nimotuzumab (powder), a strong antitumor agent, is cytolytic on target tumors by its capacity to cause antibody dependent cell mediated cytotoxicity (ADCC) and complement dependent cytotoxicity (CDC).

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 780758-10-3
Molecular Weight:147.58 kDa

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (257 KB)

Nimotuzumab (powder) Chemical Structure

CAS. Nr.: 780758-10-3

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Menge

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Other In-stock Forms of Nimotuzumab (powder)

Nimotuzumab

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Use of MCE Products

Antibody-Drug Conjugates

One-stop solution for XDC (ADC/PDC/RDC/ApDC/FDC/ISAC/VDC/SMDC)

Biologische Aktivität
- Beschreibung
- Conjugated
- Reconstitution
- Format
- Anwendung
Chemical Information
Publications (1)
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Alle EGFR Isoform-spezifische Produkte anzeigen :

Conjugated

Unconjugated

Reconstitution

The product can be reconstituted/diluted with sterile PBS or saline.

Format

IgG1-kappa

Anwendung

ELISA, FACS, Functional assay

Chemical Information

CAS. Nr. 780758-10-3
Molecular Weight 147.58 kDa
SMILES

[Nimotuzumab (powder)]
Formulation

Please refer to the lot-specific COA for specific buffer information.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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Journal Impact Factor

Cell Rep Med

DDX5 super-enhancer promotes vasculogenic mimicry formation and metastasis in nasopharyngeal carcinoma by enhancing ADAM10 transcription. [Abstract]

2025 Jun 17;6(6):102146. PMID: 40412383

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (257 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Inhibitory Antibodies User Guide (603 KB)

Verweise

[1]. Zaima Mazorra, et al. Nimotuzumab Induces NK Cell Activation, Cytotoxicity, Dendritic Cell Maturation and Expansion of EGFR-Specific T Cells in Head and Neck Cancer Patients. Front Pharmacol. 2017 Jun 19;8:382. [Content Brief]

[2]. Melarkode S Ramakrishnan, et al. Nimotuzumab, a promising therapeutic monoclonal for treatment of tumors of epithelial origin. MAbs. Jan-Feb 2009;1(1):41-8. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

Nimotuzumab (powder)

1 Cited Publications

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100 mg

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Biologische Aktivität
- Beschreibung
- Conjugated
- Reconstitution
- Format
- Anwendung
Chemical Information
Publications (1)
Reinheit & Dokumentation
Verweise

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Art. -Nr.:
Menge:
MCE Japan Authorized Agent:

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CAS. Nr.:
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Nimotuzumab (powder)

Other In-stock Forms of Nimotuzumab (powder)

Publications Citing Use of MedChemExpress (MCE) Nimotuzumab (powder)

Alle EGFR Isoform-spezifische Produkte anzeigen