2. Metabolic Enzyme/Protease
  3. Indoleamine 2,3-Dioxygenase (IDO)
  4. NLG802

NLG802 is a proagent of indoximod, an orally active indoleamine 2,3-dioxygenase (IDO) inhibitor.

For research use only. We do not sell to patients.

NLG802 Chemical Structure

NLG802 Chemical Structure

CAS No. : 2071683-99-1

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Based on 1 publication(s) in Google Scholar

NLG802 Related Antibodies

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View All Indoleamine 2,3-Dioxygenase (IDO) Isoform Specific Products:

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IDO1 IDO2 IDO

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

NLG802 is a proagent of indoximod, an orally active indoleamine 2,3-dioxygenase (IDO) inhibitor.

Clinical Trial
Molecular Weight

395.92

Formula

C20H30ClN3O3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CC(C)C[C@H](N)C(N[C@@H](C(OCC)=O)CC1=CN(C)C2=CC=CC=C12)=O.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (631.44 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5258 mL 12.6288 mL 25.2576 mL
5 mM 0.5052 mL 2.5258 mL 5.0515 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.5258 mL 12.6288 mL 25.2576 mL 63.1441 mL
5 mM 0.5052 mL 2.5258 mL 5.0515 mL 12.6288 mL
10 mM 0.2526 mL 1.2629 mL 2.5258 mL 6.3144 mL
15 mM 0.1684 mL 0.8419 mL 1.6838 mL 4.2096 mL
20 mM 0.1263 mL 0.6314 mL 1.2629 mL 3.1572 mL
25 mM 0.1010 mL 0.5052 mL 1.0103 mL 2.5258 mL
30 mM 0.0842 mL 0.4210 mL 0.8419 mL 2.1048 mL
40 mM 0.0631 mL 0.3157 mL 0.6314 mL 1.5786 mL
50 mM 0.0505 mL 0.2526 mL 0.5052 mL 1.2629 mL
60 mM 0.0421 mL 0.2105 mL 0.4210 mL 1.0524 mL
80 mM 0.0316 mL 0.1579 mL 0.3157 mL 0.7893 mL
100 mM 0.0253 mL 0.1263 mL 0.2526 mL 0.6314 mL
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NLG802 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NLG8022071683-99-1NLG 802NLG-802Indoleamine 2,3-Dioxygenase (IDO)Inhibitorinhibitorinhibit

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