NM-002
NM-002 is a metabolite of prodrug NM-001 (HY-178819), with NIR emission. NM-002 generates through activates the prodrug NM-001 by overexpressed Cathepsin B (CTSB) within tumor cells. NM-002 has no toxicity towards tumor cells and can escape from the lysosomes into the cytoplasm. NM-002 can be used for real-time drug release monitoring research.
For research use only. We do not sell to patients.
- Formula: C65H81ClN14O16
- Molecular Weight:1349.88
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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Molecular Weight 1349.88
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Formula C65H81ClN14O16
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SMILES
OC1=CC=C(C[C@@H](NC([C@@H](NC2=O)CC(O)=O)=O)C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(NC2)=O)=O)CCCCNC(CCC3=CN(CCOCCOCCOCCOC4=CC(OC(/C=C/C5=CC(Cl)=C(O)C(CO)=C5)=C/C6=C(C#N)/C#N)=C6C=C4C(C)(C)C)N=N3)=O)=O)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NM-002 Related Classifications
HY-178820 Related Classifications
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