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Cat. No.: HY-182387

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NM404

NM404 is a targeted radionuclide processing agent with slow clearance. Radioiodine-labeled NM404 is a small-molecule phospholipid ether analog that exhibits significant tumor uptake capacity and persistent tumor retention properties in more than 45 spontaneous and xenograft tumor models.

For research use only. We do not sell to patients.

CAS No.: 208986-26-9
Formula: C₂₉H₅₃INO₄P
Molecular Weight:637.61

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

NM404 Chemical Structure

CAS No.: 208986-26-9

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One-Stop Platform：From Independent R&D to Pilot-Scale Production

Biological Activity
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- Clinical Trial
Chemical Information
Purity & Documentation
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Biological Activity

Description

All Radionuclide-Drug Conjugates (RDCs) Isoforms :

Clinical Trial

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991	Plexxikon\|		2011-05	PHASE1

Chemical Information

CAS No. 208986-26-9
Molecular Weight 637.61
Formula C₂₉H₅₃INO₄P
SMILES

O=P(OCCCCCCCCCCCCCCCCCCC1=CC=C(C=C1)I)(OCC[N+](C)(C)C)[O-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Grudzinski JJ, et al. Application of a whole-body pharmacokinetic model for targeted radionuclide therapy to NM404 and FLT. Phys Med Biol. 2012;57(6):1641-1657. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- Clinical Trial
Chemical Information
Purity & Documentation
References

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NM404

All Radionuclide-Drug Conjugates (RDCs) Isoforms