NS004
Based on 1 Customer Validation
NS004 is a potassium (BK) channel activator that increases Iberiotoxin (HY-P0190) or Tetraethylammonium (HY-B1793)-sensitive whole-cell efflux currents. NS004 also significantly increased the activity of individual GH3 cell BK channels and rat brain BK channels reorganized into planar lipid bilayers, causing an increase in channel mean open time, a decrease in intermittent time, and an increase in channel voltage/calcium sensitivity.
For research use only. We do not sell to patients.
- Purity: 99.67%
- CAS No.: 141797-92-4
- Formula: C14H8ClF3N2O2
- Molecular Weight:328.67
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Chemical Information
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CAS No. 141797-92-4
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Appearance Solid
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Molecular Weight 328.67
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Formula C14H8ClF3N2O2
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Color White to off-white
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SMILES
O=C1N(C2=CC=C(C=C2N1)C(F)(F)F)C3=CC(Cl)=CC=C3O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 125 mg/mL (380.32 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.0426 mL | 15.2128 mL | 30.4257 mL | 76.0641 mL |
| 5 mM | 0.6085 mL | 3.0426 mL | 6.0851 mL | 15.2128 mL | |
| 10 mM | 0.3043 mL | 1.5213 mL | 3.0426 mL | 7.6064 mL | |
| 15 mM | 0.2028 mL | 1.0142 mL | 2.0284 mL | 5.0709 mL | |
| 20 mM | 0.1521 mL | 0.7606 mL | 1.5213 mL | 3.8032 mL | |
| 25 mM | 0.1217 mL | 0.6085 mL | 1.2170 mL | 3.0426 mL | |
| 30 mM | 0.1014 mL | 0.5071 mL | 1.0142 mL | 2.5355 mL | |
| 40 mM | 0.0761 mL | 0.3803 mL | 0.7606 mL | 1.9016 mL | |
| 50 mM | 0.0609 mL | 0.3043 mL | 0.6085 mL | 1.5213 mL | |
| 60 mM | 0.0507 mL | 0.2535 mL | 0.5071 mL | 1.2677 mL | |
| 80 mM | 0.0380 mL | 0.1902 mL | 0.3803 mL | 0.9508 mL | |
| 100 mM | 0.0304 mL | 0.1521 mL | 0.3043 mL | 0.7606 mL |
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