NT-0249
NT-0249 is an orally active NLRP3 inhibitor. NT-0249 has anti-inflammatory activity
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- CAS. Nr.: 2763617-39-4
- Formel: C22H28N5NaO4S
- Molecular Weight:481.54
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
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NLRP3 |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Diet-Induced Obesity (DIO) in mice[1]
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Dosage:100 mg/kg
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Administration:p.o. 3 times a day for 28 days
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Result:Reduced inflammatory biomarkers sVCAM-1 and suPAR
Chemical Information
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CAS. Nr. 2763617-39-4
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Molecular Weight 481.54
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Formel C22H28N5NaO4S
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SMILES
O=C([N-]S(N(C1=CN(C)N=C1)C[C@@H]2CCCO2)(=O)=O)NC3=C4C(CCC4)=CC5=C3CCC5.[Na+]
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)