NT-0249
NT-0249 is an orally active NLRP3 inhibitor. NT-0249 has anti-inflammatory activity
For research use only. We do not sell to patients.
- CAS No.: 2763617-39-4
- Formula: C22H28N5NaO4S
- Molecular Weight:481.54
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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NLRP3 |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Diet-Induced Obesity (DIO) in mice[1]
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Dosage:100 mg/kg
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Administration:p.o. 3 times a day for 28 days
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Result:Reduced inflammatory biomarkers sVCAM-1 and suPAR
Chemical Information
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CAS No. 2763617-39-4
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Molecular Weight 481.54
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Formula C22H28N5NaO4S
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SMILES
O=C([N-]S(N(C1=CN(C)N=C1)C[C@@H]2CCCO2)(=O)=O)NC3=C4C(CCC4)=CC5=C3CCC5.[Na+]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)