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Cat. No.: HY-169807

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O-2172

O-2172, a carbacyclic analog, is a DAT inhibitor, with IC₅₀ values of 47 nM and 7000 nM for DAT and SERT, respectively.

For research use only. We do not sell to patients.

CAS No.: 521062-92-0
Formula: C₁₄H₁₆Cl₂O₂
Molecular Weight:287.18

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

O-2172 Chemical Structure

CAS No.: 521062-92-0

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

O-2172, a carbacyclic analog, is a DAT inhibitor, with IC₅₀ values of 47 nM and 7000 nM for DAT and SERT, respectively^[1].

Chemical Information

CAS No. 521062-92-0
Molecular Weight 287.18
Formula C₁₄H₁₆Cl₂O₂
SMILES

O=C(C(C1CCCC1)C2=CC=C(C(Cl)=C2)Cl)OC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Peter C Meltzer, et al. Synthesis and evaluation of dopamine and serotonin transporter inhibition by oxacyclic and carbacyclic analogues of methylphenidate. J Med Chem. 2003 Apr 10;46(8):1538-45. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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