Copy Link Print Information

Onartuzumab

(Synonyms: MetMAb)
2 Cited Publications
Revisión del cliente

Based on 2 publication(s) in Google Scholar

Onartuzumab (MetMAb) is a unique, humanized and affinity-matured monovalent (one-armed) monoclonal antibody against the MET receptor. Onartuzumab potently inhibits HGF binding and receptor phosphorylation and signaling. Onartuzumab has antibody-like pharmacokinetics and antitumor activity.

Para uso exclusivo en investigación. No vendemos a pacientes.

  • Pureza: 99.62%
  • No. CAS: 1133766-06-9
  • Peso molecular:98.907 kDa
  • Almacenamiento:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Onartuzumab
  • Experimental Validation Results for Onartuzumab
  • Experimental Validation Results for Onartuzumab
  • Onartuzumab Chemical Structure
    Onartuzumab Chemical Structure
No. CAS: 1133766-06-9
Tamaño
Precio
Stock
Cantidad
Amount: USD 0.00
Please select quantity
or
or

* Seleccione Cantidad antes de agregar artículos.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download
Onartuzumab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Encuentre su distribuidor local Your local distributor: Hycultec GmbHHycultec
  • Actividad biológica
  • Chemical Information
  • Pureza y Documentación
  • Referencias
  • Help & FAQs
Top Publications Citing

Use of MCE Products

Publications Citing Use of MedChemExpress (MCE) Onartuzumab

More
Keywords
MOQ
Minimum order quantity
100 mg

Obtener un presupuesto En stock

Other size
Obtener un presupuesto
Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress Inicie sesiòn
Registrar
Sign in to MedChemExpress
Registrar una cuenta nueva

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • 1/16

    (Fab-G1-kappa)-(Fc-G1)

  • 1/16

    Immobilized Onartuzumab can bind Human c-MET/HGFR Protein (ECD, His Tag). The EC50 for this effect is 4.21 ng/mL.

  • 1/16

    Flow cytometric analysis of 1.5×106 MDA-MB-231 cells with Onartuzumab (HY-P99250, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Onartuzumab Chemical Structure
    1/16
  • Onartuzumab
  • Immobilized Onartuzumab can bind Human c-MET/HGFR Protein (ECD, His Tag). The EC50 for this effect is 4.21 ng/mL.
  • Flow cytometric analysis of 1.5×106 MDA-MB-231 cells with Onartuzumab (HY-P99250, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • (Fab-G1-kappa)-(Fc-G1)