p-Hydroxyphenylacetone
p-Hydroxyphenylacetone, a Raspberry ketone (HY-N1426) derivative, is an androgen receptor (AR) antagonist with an IC50 of 420 μM in MDA-kb2 human breast cancer cells. p-Hydroxyphenylacetone can be used for breast cancer research.
For research use only. We do not sell to patients.
- CAS No.: 770-39-8
- Formula: C9H10O2
- Molecular Weight:150.17
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
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Help & FAQs
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HY-113121
Vanillylmandelic acidAntioxidant Agent -
HY-113121R
Vanillylmandelic acid (Standard)Antioxidant Agent -
HY-W015675
4-Hydroxycyclohexanecarboxylic acid -
HY-33528
4-Hydroxyphthalic acidMetal-organic Framework -
HY-101416
Vanilpyruvic acidCatecholamine Metabolite -
HY-W015675R
4-Hydroxycyclohexanecarboxylic acid (Standard) -
HY-101416R
Vanilpyruvic acid (Standard)Catecholamine Metabolite
Biological Activity
Description
Chemical Information
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CAS No. 770-39-8
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Molecular Weight 150.17
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Formula C9H10O2
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SMILES
O=C(CC1=CC=C(C=C1)O)C
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Structure Classification
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
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Research Protocol for Endocrine Diseases
Endocrine diseases often arise from disrupted hormone production, hormone signaling, or target-tissue responsiveness; for diabetes-focused endocrine disease models, insulin signaling regulates glucose uptake, hepatic glucose output, lipid metabolism, and β-cell compensation. Type 2 diabetes develops through interacting defects in insulin resistance, β-cell dysfunction, adipose inflammation, hepatic glucose overproduction, altered incretin signaling, and ectopic lipid metabolism. A major unresolved question is whether endocrine dysfunction is driven primarily by target-tissue insulin resistance, intrinsic β-cell failure, immune/inflammatory stress, or combined multi-organ failure that differs by disease stage.
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Breast Cancer Modeling
Breast cancer is a heterogeneous cancer, and it has been distinguished into four subtypes: luminal A, luminal B, HER2-positive and basal-like. Molecular mutations, epigenetic alterations, hormone exposure and immune microenvironment are related to the progression of breast cancer.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
p-Hydroxyphenylacetone Related Classifications
HY-W087006 Related Classifications
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