PAD-IN-4
PAD-IN-4 is a potent PAD inhibitor (PAD 1/4, IC50 = 0.273/0.24 μM). PAD-IN-4 shows no significant cytotoxicity against A549 or MDA-MB-231 cells. PAD-IN-4 can be used for the study of cancer and autoimmune diseases.
For research use only. We do not sell to patients.
- Formula: C25H27ClN4O3
- Molecular Weight:466.96
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
PAD-IN-4 (Compound 13) (1-1000 μM, 48 h) shows no significant cytotoxicity against A549 or MDA-MB-231 cells, and its CC50 value is greater than 200 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:A549 cells, MDA-MB-231 cells
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Concentration:1 μM, 10 μM, 100 μM, 1000 μM
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Incubation Time:48 h
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Result:Showed no significant cytotoxicity against A549 or MDA-MB-231 cells, and its CC50 value is greater than 200 μM.
Chemical Information
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Molecular Weight 466.96
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Formula C25H27ClN4O3
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SMILES
O=C(N[C@@H](CCCNC(CCl)=N)C(NCC1=CC=CC=C1)=O)C2=CC=C3C=C(O)C=CC3=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)