PAR4 antagonist 2
PAR4 antagonist 2 (Compound 31) is a protease activated receptor 4 (PAR4) antagonist, with IC50 values of 95 nM and 367 nM for human PAR4 and mouse PAR4. PAR4 antagonist 2 is active against PAR4 activation by the native protease thrombin cleavage but not the synthetic PAR4 agonist peptide AYPGKF.
For research use only. We do not sell to patients.
- Formula: C22H18F2N6O
- Molecular Weight:420.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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PAR4 |
Chemical Information
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Molecular Weight 420.41
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Formula C22H18F2N6O
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SMILES
O=C(NC1=NNC(C2=C(F)C=C(F)C=C2)=N1)C3=NN(C4=CC=CC=C4)C5=C3CCCC5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)