2. Cell Cycle/DNA Damage Epigenetics
  3. PARP
  4. PARP-1-IN-13

PARP-1-IN-13 (Compound 19c) is a PARP-1 inhibitor (IC50: 26 nM). PARP-1-IN-13 inhibits DNA single-strand breakage repair and aggravates DNA double-strand breakage. PARP-1-IN-13 promotes the apoptosis of cancer cells through the mitochondrial apoptosis pathway.

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PARP-1-IN-13

PARP-1-IN-13 Chemical Structure

CAS No. : 2999661-74-2

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PARP-1-IN-13 Related Antibodies

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Description

PARP-1-IN-13 (Compound 19c) is a PARP-1 inhibitor (IC50: 26 nM). PARP-1-IN-13 inhibits DNA single-strand breakage repair and aggravates DNA double-strand breakage. PARP-1-IN-13 promotes the apoptosis of cancer cells through the mitochondrial apoptosis pathway[1].

IC50 & Target

26 nM (PARP-1)[1]
Masse moléculaire

391.45

Formule

C20H17N5O2S
CAS No.
SMILES

O=C1NC(C2=CC=C(/C=N/NC(NCC)=S)C=C2)=NC3=C1OC4=C3C=CC=C4
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

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Références
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PARP-1-IN-13 Related Classifications

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Keywords:

PARP-1-IN-132999661-74-2PARPpoly ADP ribose polymerasecancerDNA breakagemitochondrialInhibitorinhibitorinhibit

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HY-155122
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