PBK-IN-9
Based on 1 Customer Validation
PBK-IN-9 is a potent PDZ-binding kinase (PBK) inhibitor with an IC50 of 0.64 nM. PBK-IN-9 can be used for research on breast cancer, lung cancer, bladder cancer and prostate cancer.
For research use only. We do not sell to patients.
- Purity: 98.45%
- CAS No.: 1338540-55-8
- Formula: C20H18N2O2S
- Molecular Weight:350.43
-
Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
-
Cell Cycle/DNA Damage Compound Library
HY-L004
-
Kinase Inhibitor Library
HY-L009
-
Anti-Cancer Compound Library
HY-L025
-
Anti-Aging Compound Library
HY-L034
-
Anti-Breast Cancer Compound Library
HY-L074
-
Anti-Lung Cancer Compound Library
HY-L075
-
Anti-Prostate Cancer Compound Library
HY-L124
-
Bioactive Compound Library Max
HY-L181
-
Anti-Aging Compound Library Mini
HY-L034M
-
MCE Bioactive Compound Library
HY-L001V
-
Bioactive Compound Library
HY-L001
-
Protein Kinase Compound Library
HY-L196
-
High-Throughput Bioactive Compound Library
HY-L205
Biological Activity
PBK-IN-9 (Compound 1160) (72 h) inhibits the proliferation of BT549, T47D, A549, HT1197, and 22Rv1 cells, with IC50 values of 54, 57, 56, 230, and 69 nM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 1338540-55-8
-
Appearance Solid
-
Molecular Weight 350.43
-
Formula C20H18N2O2S
-
Color Off-white to light yellow
-
SMILES
O=C1NC2=C(C(C3=CC=C([C@@H](C)CN)C=C3)=C(O)C=C2)C4=C1SC=C4
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 10 mg/mL (28.54 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (273 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.8536 mL | 14.2682 mL | 28.5364 mL | 71.3409 mL |
| 5 mM | 0.5707 mL | 2.8536 mL | 5.7073 mL | 14.2682 mL | |
| 10 mM | 0.2854 mL | 1.4268 mL | 2.8536 mL | 7.1341 mL | |
| 15 mM | 0.1902 mL | 0.9512 mL | 1.9024 mL | 4.7561 mL | |
| 20 mM | 0.1427 mL | 0.7134 mL | 1.4268 mL | 3.5670 mL | |
| 25 mM | 0.1141 mL | 0.5707 mL | 1.1415 mL | 2.8536 mL |
Powered by Bioz