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Cat. No.: HY-161942

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PCSK9-IN-31

PCSK9-IN-31 (Compound WX002) is an orally active PCSK9 inhibitor. PCSK9-IN-31 can lower low-density lipoprotein cholesterol (LDL-C) and total cholesterol (TC) in high cholesterol fed model rats.

For research use only. We do not sell to patients.

CAS No.: 2247649-76-7
Formula: C₂₃H₂₆N₄O₃
Molecular Weight:406.48

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

PCSK9-IN-31 Chemical Structure

CAS No.: 2247649-76-7

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

PCSK9-IN-31 (Compound WX002) is an orally active PCSK9 inhibitor. PCSK9-IN-31 can lower low-density lipoprotein cholesterol (LDL-C) and total cholesterol (TC) in high cholesterol fed model rats^[1].

Chemical Information

CAS No. 2247649-76-7
Molecular Weight 406.48
Formula C₂₃H₂₆N₄O₃
SMILES

CC1=C(N([C@H]2CNCCC2)C(C3=CC=C(C4=NOC(C)(C)C4=O)C=C3)=O)N=CC=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Wenjie Xu, et al. CRYSTAL FORM α OF COMPOUND A, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION CONTAINING CRYSTAL FORM. Patent. WO2020078170A1.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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