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Art. -Nr.: HY-189212

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PCSK9-IN-38

PCSK9-IN-38 is a PCSK9 inhibitor with an IC₅₀ of 1.07 μM. PCSK9-IN-38 elevates the level of LDLR protein. PCSK9-IN-38 can be used in the study of dyslipidemia.

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CAS. Nr.: 3126488-23-8
Formel: C₂₂H₂₈N₂O₅
Molecular Weight:400.47

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

PCSK9-IN-38 Chemical Structure

CAS. Nr.: 3126488-23-8

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

PCSK9-IN-38 is a PCSK9 inhibitor with an IC₅₀ of 1.07 μM. PCSK9-IN-38 elevates the level of LDLR protein. PCSK9-IN-38 can be used in the study of dyslipidemia^[1].

In Vitro

PCSK9-IN-38 (30 min) inhibits PCSK9 with an IC₅₀ of 1.07 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 3126488-23-8
Molecular Weight 400.47
Formel C₂₂H₂₈N₂O₅
SMILES

O=C(NC1=CC=CC(NC(CCC(C)C)=O)=C1)C2=CC(OC)=C(OC)C(OC)=C2
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Wang LR, et al. Discovery, synthesis, and biological evaluation of N,N'-diacyl-m-phenylenediamine derivatives as novel PCSK9 small-molecule inhibitors. Eur J Med Chem. 2026 Nov 15;318:119188.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

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100 mg

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