PD 136450
PD 136450 (CAM 1189) is an antagonist for cholecystokinin 2 (CCK2). PD 136450 exhibits anti-secretory, anxiolytic and anti-ulcer activities, inhibits gastric acid secretion (IC50=1 mg/kg), and ameliorates the haemorrhagic lesions (IC50=4.7 mg/kg) in rats.
For research use only. We do not sell to patients.
- CAS No.: 139067-52-0
- Formula: C35H40N4O6
- Molecular Weight:612.72
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Protocols
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Description
Chemical Information
-
CAS No. 139067-52-0
-
Molecular Weight 612.72
-
Formula C35H40N4O6
-
SMILES
O=C(/C=C/C(N[C@@H](CNC([C@@](C)(CC1=CNC2=C1C=CC=C2)NC(OC3C4CC(CC3C5)CC5C4)=O)=O)C6=CC=CC=C6)=O)O
-
Synonyms
CAM 1189
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
-
Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PD 136450 Related Classifications
HY-120381 Related Classifications
Powered by Bioz