1. Metabolic Enzyme/Protease
  2. Phosphodiesterase (PDE)
  3. PDE4-IN-9

PDE4-IN-9 

Cat. No.: HY-146974
Handling Instructions

PDE4-IN-9 (Compound 5j) is a potent inhibitor of PDE4. PDE4-IN-9 exhibits lower IC50 value (1.4 μM) against PDE4 than parent rolipram (2.0 μM) in in vitro enzyme assay. PDE4-IN-9 also displays good in vivo activity in animal models of asthma/COPD and sepsis induced by LPS.

For research use only. We do not sell to patients.

PDE4-IN-9 Chemical Structure

PDE4-IN-9 Chemical Structure

CAS No. : 2519450-32-7

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Description

PDE4-IN-9 (Compound 5j) is a potent inhibitor of PDE4. PDE4-IN-9 exhibits lower IC50 value (1.4 μM) against PDE4 than parent rolipram (2.0 μM) in in vitro enzyme assay. PDE4-IN-9 also displays good in vivo activity in animal models of asthma/COPD and sepsis induced by LPS[1].

Molecular Weight

328.35

Formula

C15H12N4O3S

CAS No.
SMILES

COC1=CC=C(C=C1)C2=NC(C(N3CCS/C3=N\C#N)=O)=CO2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
PDE4-IN-9
Cat. No.:
HY-146974
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