PDE4-IN-9
PDE4-IN-9 (Compound 5j) is a potent inhibitor of PDE4. PDE4-IN-9 exhibits lower IC50 value (1.4 μM) against PDE4 than parent rolipram (2.0 μM) in in vitro enzyme assay. PDE4-IN-9 also displays good in vivo activity in animal models of asthma/COPD and sepsis induced by LPS.
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- CAS. Nr.: 2519450-32-7
- Formel: C15H12N4O3S
- Molecular Weight:328.35
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Beschreibung
Chemical Information
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CAS. Nr. 2519450-32-7
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Molecular Weight 328.35
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Formel C15H12N4O3S
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SMILES
COC1=CC=C(C=C1)C2=NC(C(N3CCS/C3=N\C#N)=O)=CO2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
PDE4-IN-9 Related Classifications
HY-146974 Related Classifications
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