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  2. PROTAC Linker
  3. PEG6-(CH2CO2H)2

PEG6-(CH2CO2H)2 

Cat. No.: HY-122702 Purity: >95.0%
Handling Instructions

PEG6-(CH2CO2H)2 is a symmetric PEG PROTAC linker, for the synthesis of Homo-PROTACs which is bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation.

For research use only. We do not sell to patients.

PEG6-(CH2CO2H)2 Chemical Structure

PEG6-(CH2CO2H)2 Chemical Structure

CAS No. : 77855-76-6

Size Price Stock Quantity
50 mg USD 100 In-stock
Estimated Time of Arrival: December 31
100 mg USD 160 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
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Description

PEG6-(CH2CO2H)2 is a symmetric PEG PROTAC linker, for the synthesis of Homo-PROTACs which is bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation[1].

IC50 & Target

PEGs

 

Molecular Weight

354.35

Formula

C₁₄H₂₆O₁₀

CAS No.

77855-76-6

SMILES

O=C(O)COCCOCCOCCOCCOCCOCC(O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

Ethanol : 100 mg/mL (282.21 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8221 mL 14.1103 mL 28.2207 mL
5 mM 0.5644 mL 2.8221 mL 5.6441 mL
10 mM 0.2822 mL 1.4110 mL 2.8221 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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  • Molarity Calculator

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The molarity calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

PEG6-(CH2CO2H)2PROTAC LinkerInhibitorinhibitorinhibit

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Product Name:
PEG6-(CH2CO2H)2
Cat. No.:
HY-122702
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