Pemivibart
Based on 1 Customer Validation
Pemivibart is an anti-SARS-CoV-2 human IgG1 λ2 monoclonal antibody. Recommend Isotype Controls: Human IgG1 lambda2, Isotype Control (HY-P990096).
For research use only. We do not sell to patients.
- Purity: 99.12%
- CAS No.: 2858673-18-2
- Molecular Weight:144.788 kDa
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Human IgG1 lambda2
Virus
SARS-CoV-2
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
YP_009724390.1
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
-
Human IgG1 lambda2
ELISA, FACS, Functional assay
-
Loaded Pemivibart on AHC2 biosensor, can bind SARS-CoV-2 S Protein RBD (sf9, His, HY-P73664) with an affinity constant of 4.334E-09 M as determined in BLI assay. -
Immobilized SARS-CoV-2 S Protein RBD (sf9, His, HY-P73664) can bind Pemivibart. The EC50 for this effect is 2.165 ng/mL.
Chemical Information
-
CAS No. 2858673-18-2
-
Appearance Liquid
-
Molecular Weight 144.788 kDa
-
Color Colorless to light yellow
-
Shipping
Shipping with dry ice.
-
Formulation
Please refer to the lot-specific COA for specific buffer information.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
-
Data Sheet (253 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Inhibitory Antibodies User Guide (603 KB)
References
[1]. Pemivibart
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)