Pent-4-ynal
Based on 1 Customer Validation
Pent-4-ynal is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity : 97.63%
- CAS No.: 18498-59-4
- Formula: C5H6O
- Molecular Weight:82.10
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Storage:
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
All PROTAC Linkers Isoforms
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Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E790 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 18498-59-4
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Appearance Liquid
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Molecular Weight 82.10
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Formula C5H6O
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SMILES
O=CCCC#C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (1218.03 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (242 KB)
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SDS (392 KB)
- English - EN (392 KB)
- Français - FR (392 KB)
- Deutsch - DE (392 KB)
- Norwegian - NO (392 KB)
- Español - ES (392 KB)
- Swedish - SV (392 KB)
- Italian - IT (392 KB)
- Korean - KR (392 KB)
- Portuguese - PT (392 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 12.1803 mL | 60.9013 mL | 121.8027 mL | 304.5067 mL |
| 5 mM | 2.4361 mL | 12.1803 mL | 24.3605 mL | 60.9013 mL | |
| 10 mM | 1.2180 mL | 6.0901 mL | 12.1803 mL | 30.4507 mL | |
| 15 mM | 0.8120 mL | 4.0601 mL | 8.1202 mL | 20.3004 mL | |
| 20 mM | 0.6090 mL | 3.0451 mL | 6.0901 mL | 15.2253 mL | |
| 25 mM | 0.4872 mL | 2.4361 mL | 4.8721 mL | 12.1803 mL | |
| 30 mM | 0.4060 mL | 2.0300 mL | 4.0601 mL | 10.1502 mL | |
| 40 mM | 0.3045 mL | 1.5225 mL | 3.0451 mL | 7.6127 mL | |
| 50 mM | 0.2436 mL | 1.2180 mL | 2.4361 mL | 6.0901 mL | |
| 60 mM | 0.2030 mL | 1.0150 mL | 2.0300 mL | 5.0751 mL | |
| 80 mM | 0.1523 mL | 0.7613 mL | 1.5225 mL | 3.8063 mL | |
| 100 mM | 0.1218 mL | 0.6090 mL | 1.2180 mL | 3.0451 mL |