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Cat. No.: HY-15502

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PF-3635659

Name: PF-3635659
Brand: MedChemExpress
SKU: HY-15502
Price: 492.00 USD
Availability: InStock
Rating: 5 (1 reviews)

PF-3635659 is a potent antagonist of the muscarinic M3 receptor (mAChR3). PF-3635659 can be used for chronic obstructive pulmonary disease (COPD) research.

For research use only. We do not sell to patients.

CAS No.: 931409-24-4
Formula: C₂₈H₃₂N₂O₃
Molecular Weight:444.57

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

PF-3635659 Chemical Structure

CAS No.: 931409-24-4

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

PF-3635659 is a potent antagonist of the muscarinic M3 receptor (mAChR3). PF-3635659 can be used for chronic obstructive pulmonary disease (COPD) research^[1].

IC₅₀ & Target

mAChR3

All mAChR Isoforms :

Chemical Information

CAS No. 931409-24-4
Molecular Weight 444.57
Formula C₂₈H₃₂N₂O₃
SMILES

O=C(C(C1=CC=CC=C1)(CCC(C)(C)N2CC(C2)OC3=CC(O)=CC=C3)C4=CC=CC=C4)N
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Dillon B R, et al.Development of a Scaleable Synthesis of a Geminal Dimethyl Tertiary Amine as an Inhaled Muscarinic Antagonist for the Treatment of COPD[J].Organic Process Research & Development, 2012, 16(2):195-203.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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PF-3635659

All mAChR Isoforms