PF-3837
PF-3837 is an Mps1 kinase inhibitor with a Ki value of 0.33 nM and an IC50 value of 5.5 nM. PF-3837 interferes with the cell cycle checkpoint by inhibiting Mps1 catalytic activity, reducing genomic stability, thereby inducing cancer cell apoptosis (Apoptosis). PF-3837 can be used in research on breast cancer.
For research use only. We do not sell to patients.
- CAS No.: 2772910-13-9
- Formula: C21H26N8O2
- Molecular Weight:422.48
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 2772910-13-9
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Molecular Weight 422.48
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Formula C21H26N8O2
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SMILES
N#CC1=CNC2=NC(NC3=CC=C(N4CCOCC4)N=C3C)=NC(NC(C)(CO)C)=C12
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)