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Cat. No.: HY-117838

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Phosphodiesterase 10-IN-2

Phosphodiesterase 10-IN-2 (THPP-4) is an oral active phosphodiesterase 10A (PDE10A) inhibitor with the K_i of 4.5 nM. Phosphodiesterase 10-IN-2 can be used for study of schizophrenia.

For research use only. We do not sell to patients.

CAS No.: 1257051-56-1
Formula: C₂₀H₂₁ClN₆O₂
Molecular Weight:412.87

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

Phosphodiesterase 10-IN-2 Chemical Structure

CAS No.: 1257051-56-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Phosphodiesterase 10-IN-2 (THPP-4) is an oral active phosphodiesterase 10A (PDE10A) inhibitor with the K_i of 4.5 nM. Phosphodiesterase 10-IN-2 can be used for study of schizophrenia^[1].

All Phosphodiesterase (PDE) Isoforms :

Chemical Information

CAS No. 1257051-56-1
Molecular Weight 412.87
Formula C₂₀H₂₁ClN₆O₂
SMILES

O=C(C1=CN(C=N1)C)N2CCC3=NC(C4=CC=C(N=C4)Cl)=NC(OC(C)C)=C3C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Raheem IT, et al. Discovery of tetrahydropyridopyrimidine phosphodiesterase 10A inhibitors for the treatment of schizophrenia. Bioorg Med Chem Lett. 2012 Sep 15;22(18):5903-8. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Chemical Information
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Phosphodiesterase 10-IN-2

All Phosphodiesterase (PDE) Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Phosphodiesterase 10-IN-2 Related Classifications

HY-117838 Related Classifications