Photoclick cholesterol
Photoclick cholesterol is a photoreactive cholesterol analog capable of undergoing click reactions. Photoclick cholesterol enables specific, saturable photoaffinity labeling of the mitochondrial translocator protein TSPO.
For research use only. We do not sell to patients.
- CAS No.: 1485490-47-8
- Formula: C30H46N2O3
- Molecular Weight:482.70
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Storage:
Solution, -20°C, 2 years
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Photoclick cholesterol (10-25 μM; 30 min dark incubation, 10 min UV irradiation) binds directly and competitively to native 18 kDa TSPO in mitochondria-enriched fractions from MA-10 mouse tumour Leydig cells, with increased labelling at 25 μM compared to 10 μM, and reduced labelling in the presence of 20- or 65-fold molar excess cholesterol[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1485490-47-8
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Appearance Liquid
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Molecular Weight 482.70
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Formula C30H46N2O3
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Color Colorless to light yellow
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SMILES
C[C@]12[C@@](C[C@H](CC2)O)([H])C3(N=N3)C[C@]4([H])[C@]1([H])CC[C@]5([C@@]4([H])CC[C@]5([H])[C@H](C)CCC(OCCCCC#C)=O)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Solution, -20°C, 2 years
Purity & Documentation
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Data Sheet (265 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Photoclick cholesterol Related Classifications
HY-W782122 Related Classifications
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