PIM-IN-1
PIM-IN-1 is a pan-PIM kinase inhibitor (KG-1, EC50 = 61 nM; pS6, EC50 = 71 nM).
For research use only. We do not sell to patients.
- Formula: C15H18ClFN4O
- Molecular Weight:324.78
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Size
Price
Stock
Quantity
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
PIM-IN-1 is a pan-PIM kinase inhibitor (KG-1, EC50 = 61 nM; pS6, EC50 = 71 nM).
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| KG-1 | EC50 |
61 nM
Compound: 27
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Cytotoxicity against human KG-1 cells assessed as reduction in cell viability
Cytotoxicity against human KG-1 cells assessed as reduction in cell viability
|
[PMID: 33096160] |
| KG-1 | EC50 |
7230 nM
Compound: 25
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Cytotoxicity against human KG-1 cells assessed as reduction in cell viability
Cytotoxicity against human KG-1 cells assessed as reduction in cell viability
|
[PMID: 33096160] |
Chemical Information
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Molecular Weight 324.78
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Formula C15H18ClFN4O
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SMILES
O=C(C1=CC(Cl)=C2C(N([C@H]([C@@]3(F)CNCC3)C)C=C2C)=N1)N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Select Batch:
Purity:
99.98%
Assay:
99.98%
ee.:
99.98%
References
Calculators
Molarity Calculator
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
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Dilution Calculator
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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