PIM-IN-1
PIM-IN-1 is a pan-PIM kinase inhibitor (KG-1, EC50 = 61 nM; pS6, EC50 = 71 nM).
Para uso exclusivo en investigación. No vendemos a pacientes.
- Fòrmula: C15H18ClFN4O
- Peso molecular:324.78
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Actividad biológica
Descripciòn
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| KG-1 | EC50 |
61 nM
Compound: 27
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Cytotoxicity against human KG-1 cells assessed as reduction in cell viability
Cytotoxicity against human KG-1 cells assessed as reduction in cell viability
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[PMID: 33096160] |
| KG-1 | EC50 |
7230 nM
Compound: 25
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Cytotoxicity against human KG-1 cells assessed as reduction in cell viability
Cytotoxicity against human KG-1 cells assessed as reduction in cell viability
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[PMID: 33096160] |
Chemical Information
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Peso molecular 324.78
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Fòrmula C15H18ClFN4O
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SMILES
O=C(C1=CC(Cl)=C2C(N([C@H]([C@@]3(F)CNCC3)C)C=C2C)=N1)N
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PIM-IN-1 Related Classifications
HY-142656 Related Classifications
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