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Cat. No.: HY-14290AR

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Pinacidil monohydrate (Standard)

Name: Pinacidil monohydrate (Standard)
Brand: MedChemExpress
SKU: HY-14290AR
Price: 100.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: P-1134 monohydrate (Standard))

Pinacidil (monohydrate) (Standard) is the analytical standard of Pinacidil (monohydrate). This product is intended for research and analytical applications. Pinacidil (P-1134) monohydrate is a potent activator of ATP-sensitive potassium channel. Pinacidil monohydrate is an antihypertensive agent hyperpolarizes vascular smooth muscle by opening K+ channels. Pinacidil monohydrate enhances K+-efflux in smooth muscle. Pinacidil monohydrate has vasorelaxant properties. Pinacidil monohydrate is able to inhibit spontaneous tone and of reducing agonist induced contractions. Pinacidil monohydrate can be studied in research area such as cardiovascular diseases.

For research use only. We do not sell to patients.

Purity: 98%
CAS No.: 85371-64-8
Formula: C₁₃H₂₁N₅O
Molecular Weight:263.34

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Pinacidil monohydrate (Standard) Chemical Structure

CAS No.: 85371-64-8

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Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 85371-64-8
Molecular Weight 263.34
Formula C₁₃H₂₁N₅O
SMILES

[H]O[H].CC(C)(C)C(N/C(NC#N)=N/C1=CC=NC=C1)C
Synonyms

P-1134 monohydrate (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Hamilton TC, et al., Cromakalim, nicorandil and pinacidil: novel drugs which open potassium channels in smooth muscle. Gen Pharmacol. 1989;20(1):1-9. [Content Brief]

[2]. Jung-Ae Kim, et al., Activation of Na+, K+, Cl−-Cotransport Mediates Intracellular Ca2+ Increase and Apoptosis Induced by Pinacidil in HepG2 Human Hepatoblastoma Cells, Biochemical and Biophysical Research Communications, Volume 281, Issue 2, 2001, Pages 511-519, ISSN 0006-291X,

[3]. Weston, A.H., et al., In Vitro Studies on the Mode of Action of Pinacidil. Drugs 36 (Suppl 7), 10–28 (1988).

[4]. Ko Zushida, et al ., Effect of diabetes on pinacidil-induced antinociception in mice, European Journal of Pharmacology, Volume 453, Issues 2–3, 2002, Pages 209-215, ISSN 0014-2999.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Pinacidil monohydrate (Standard)