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Cat. No.: HY-P2629

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PKI (5-22)

PKI (5-22) is a specific inhibitory peptide targeting the catalytic subunit of protein kinase A (PKA) and contains the active region of PKI. PKI (5-22) inhibits the enzymatic activity of the PKA catalytic subunit-like protein in Trypanosoma equiperdum. PKI (5-22) can be used in the research of trypanosomiasis.

For research use only. We do not sell to patients.

CAS No.: 128022-93-5
Formula: C₈₄H₁₃₆N₂₈O₂₇
Molecular Weight:1970.18

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

PKI (5-22) Chemical Structure

CAS No.: 128022-93-5

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

All PKA Isoforms :

In Vitro

PKI (5-22) (0.3 μg) inhibits the kemptide kinase activity of purified Trypanosoma equiperdum PKA catalytic subunit-like protein at a dose of 0.3 μg^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 128022-93-5
Molecular Weight 1970.18
Formula C₈₄H₁₃₆N₂₈O₂₇
SMILES

O=C(N[C@@H]([C@H](O)C)C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H](C)C(N[C@@H](CC(O)=O)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](C)C(N[C@@H](CO)C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@H](O)C)C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(N)=O)C(N[C@@H](C)C(N[C@@H]([C@@H](C)CC)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H]([C@H](O)C)N
Sequence

Thr-Thr-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile
Sequence Shortening

TTYADFIASGRTGRRNAI
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Araujo NA, et al. Analysis of a Novel Peptide That Is Capable of Inhibiting the Enzymatic Activity of the Protein Kinase A Catalytic Subunit-Like Protein from Trypanosoma equiperdum. The protein journal. 2023 Dec;42(6):709-727. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References

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PKI (5-22)

All PKA Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

PKI (5-22) Related Classifications

HY-P2629 Related Classifications