PknB-IN-3
PknB-IN-3 is a Mycobacterium tuberculosis Protein kinase B (PknB) inhibitor with an IC50 of 0.06 μM. PknB-IN-3 inhibits growth of Mycobacterium tuberculosis and can be used for the research of tuberculosis.
For research use only. We do not sell to patients.
- Formula: C25H29ClN2O2
- Molecular Weight:424.96
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
PknB-IN-3 (Compound 4b) potently inhibits purified recombinant M. tuberculosis PknB protein with an IC50 of 0.06 μM[1].
PknB-IN-3 (0.1-100 μg/mL; 7 days) inhibits the growth of M. tuberculosis H37Ra with an MIC of 3.1 μg/mL[1].
PknB-IN-3 (12.50 μg/mL) exhibits no detectable cytotoxicity toward Caco-2 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 424.96
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Formula C25H29ClN2O2
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SMILES
CCCCN(CC(CN1C=C(C2=C1C=CC=C2)/C=C/C(C3=CC=C(C=C3)Cl)=O)O)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PknB-IN-3 Related Classifications
HY-183726 Related Classifications
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