2. Anti-infection Metabolic Enzyme/Protease
  3. Bacterial Ser/Thr Kinase
  4. PknB-IN-3

PknB-IN-3 is a Mycobacterium tuberculosis Protein kinase B (PknB) inhibitor with an IC50 of 0.06 μM. PknB-IN-3 inhibits growth of Mycobacterium tuberculosis and can be used for the research of tuberculosis.

For research use only. We do not sell to patients.

PknB-IN-3

PknB-IN-3 Chemical Structure

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PknB-IN-3 Related Antibodies

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Description

PknB-IN-3 is a Mycobacterium tuberculosis Protein kinase B (PknB) inhibitor with an IC50 of 0.06 μM. PknB-IN-3 inhibits growth of Mycobacterium tuberculosis and can be used for the research of tuberculosis[1].

In Vitro

PknB-IN-3 (Compound 4b) potently inhibits purified recombinant M. tuberculosis PknB protein with an IC50 of 0.06 μM[1].
PknB-IN-3 (0.1-100 μg/mL; 7 days) inhibits the growth of M. tuberculosis H37Ra with an MIC of 3.1 μg/mL[1].
PknB-IN-3 (12.50 μg/mL) exhibits no detectable cytotoxicity toward Caco-2 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

PknB-IN-3 Related Antibodies
Molecular Weight

424.96

Formula

C25H29ClN2O2
SMILES

CCCCN(CC(CN1C=C(C2=C1C=CC=C2)/C=C/C(C3=CC=C(C=C3)Cl)=O)O)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PknB-IN-3 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PknB-IN-3BacterialSer/Thr KinaseProtein Serine-Threonine KinaseMycobacterium tuberculosisintestinal epithelial cellsMycobacterium tuberculosis H37RaPknBMycobacterium tuberculosis H37RvProtein kinase BCaco-2 cellstuberculosisInhibitorinhibitorinhibit

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