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PMQA (Synonyms: Zn-green)

Cat. No.: HY-D1264
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PMQA (Zn-green), an 8-aminoquinoline-based ratiometric fluorescent sensor, demonstrates the Zn2+-induced redshift of emission (85 nm). PMQA (Zn-green) is a cell membrane-permeable probe and suitable for imaging Zn2+ in living cells.

For research use only. We do not sell to patients.

PMQA Chemical Structure

PMQA Chemical Structure

CAS No. : 1263820-18-3

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Description

PMQA (Zn-green), an 8-aminoquinoline-based ratiometric fluorescent sensor, demonstrates the Zn2+-induced redshift of emission (85 nm). PMQA (Zn-green) is a cell membrane-permeable probe and suitable for imaging Zn2+ in living cells[1].

In Vitro

After incubation with PMQA (20 μM) for 1 h, weak green fluorescence appeared, presumably caused by the probe capturing intracellular zinc from its native ligands since PMQA has high affinity for zinc[1].
The response of PMQA to Zn2+ can be reversed by N,N,N’,N’-tetrakis(2-pyridylmethyl)ethylenediamine (TPEN) or EDTA[1].
When the stock solution of PMQA (0.1 mM in Tris Buffer) is kept at room temperature for a week, there is no significant loss of PMQA determined by HPLC analysis[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

292.34

Formula

C₁₇H₁₆N₄O

CAS No.

1263820-18-3

SMILES

O=C(NC1=C2N=CC=CC2=CC=C1)CNCC3=NC=CC=C3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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HY-D1264
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