PqsR-IN-1
PqsR-IN-1 (Compound 18) is a potent PqsR (Pseudomonas aeruginosa quorum sensing transcriptional regulator) inhibitor. PqsR-IN-1 attenuates pyocyanin production and has very low cytotoxicity.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2982271-62-3
- 分子式: C17H18ClN3OS
- 分子量:347.86
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- プロトコル
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
IC50 & Target
PqsR[1]
体外実験
PqsR-IN-1 (Compound 18) inhibits pqs system with IC50 values of 313 ± 156.2 nM and 342 ± 39.4 nM against two different PA strains PAO1-L and PA14, respectively[1].
PqsR-IN-1 significantly reduces pyocyanin production to 23% against a control of 0.1% DMSO at 3 × the IC50 value in P. aeruginosa strain PAO1-L[1].
PqsR-IN-1 (0-100 μM, 16 h) shows no significant toxicity to A549 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:A549 lung epithelial cells
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Concentration:0.1, 1, 12.5, 25, 50, and 100 µM
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Incubation Time:16 h
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Result:Showed no significant toxicity.
化学情報
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CAS 番号 2982271-62-3
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分子量 347.86
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分子式 C17H18ClN3OS
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SMILES
CCCCCC1=NC(CN2C=NC3=CC=C(C=C3C2=O)Cl)=CS1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
PqsR-IN-1 関連分類
HY-146705 関連分類
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