Propane sultone
Based on 1 Customer Validation
Propane sultone is a multifunctional intermediate, which can be used for the synthesis of other active compounds. Propane sultone can also be used as an additive in lithium battery electrolytes.
For research use only. We do not sell to patients.
- Purity: 99.97%
- CAS No.: 1120-71-4
- Formula: C3H6O3S
- Molecular Weight:122.14
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 1120-71-4
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Appearance <30°C Solid,>33°C Liquid
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Molecular Weight 122.14
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Formula C3H6O3S
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Color Colorless to off-white
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SMILES
O=S1(OCCC1)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 200 mg/mL (1637.47 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 5 mg/mL (40.94 mM); Clear solution
This protocol yields a clear solution of ≥ 5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 5 mg/mL (40.94 mM); Clear solution
This protocol yields a clear solution of ≥ 5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (278 KB)
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SDS (930 KB)
- English - EN (930 KB)
- Français - FR (930 KB)
- Deutsch - DE (930 KB)
- Norwegian - NO (930 KB)
- Español - ES (930 KB)
- Swedish - SV (930 KB)
- Italian - IT (930 KB)
- Korean - KR (930 KB)
- Portuguese - PT (930 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 8.1873 mL | 40.9366 mL | 81.8733 mL | 204.6832 mL |
| 5 mM | 1.6375 mL | 8.1873 mL | 16.3747 mL | 40.9366 mL | |
| 10 mM | 0.8187 mL | 4.0937 mL | 8.1873 mL | 20.4683 mL | |
| 15 mM | 0.5458 mL | 2.7291 mL | 5.4582 mL | 13.6455 mL | |
| 20 mM | 0.4094 mL | 2.0468 mL | 4.0937 mL | 10.2342 mL | |
| 25 mM | 0.3275 mL | 1.6375 mL | 3.2749 mL | 8.1873 mL | |
| 30 mM | 0.2729 mL | 1.3646 mL | 2.7291 mL | 6.8228 mL | |
| 40 mM | 0.2047 mL | 1.0234 mL | 2.0468 mL | 5.1171 mL | |
| 50 mM | 0.1637 mL | 0.8187 mL | 1.6375 mL | 4.0937 mL | |
| 60 mM | 0.1365 mL | 0.6823 mL | 1.3646 mL | 3.4114 mL | |
| 80 mM | 0.1023 mL | 0.5117 mL | 1.0234 mL | 2.5585 mL | |
| 100 mM | 0.0819 mL | 0.4094 mL | 0.8187 mL | 2.0468 mL |
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