Propargylcholine bromide
Based on 2 publication(s) in Google Scholar
Propargylcholine bromide is a choline analogue containing terminal propargyl that can be incorporated into all classes of Choline-containing phospholipids such as phosphatidylcholine and sphingomyelin, labeling Choline-containing phospholipids. Propargylcholine bromide-labeled phospholipid molecules can be visualized in cells with high sensitivity and spatial resolution. Propargylcholine bromide can be used as a molecular tool to study the biochemical and metabolic processes of Choline-containing phospholipids in cells. Propargylcholine (bromide) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
For research use only. We do not sell to patients.
- Purity: 99.97%
- CAS No.: 111755-76-1
- Formula: C7H14BrNO
- Molecular Weight:208.10
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Propargylcholine bromide
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Biological Activity
Propargylcholine bromide (10, 50 μM; 24 h) incorporates into NIH 3T3 cells and shows strong staining in a concentration-dependent manner (fixed and stained with Alexa568-azide)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:NIH 3T3 cells
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Concentration:10, 50 µM
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Incubation Time:24 h
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Result:Showed strong staining proportional in intensity to the concentration of added Propargylcholine bromide.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 111755-76-1
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Appearance Solid
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Molecular Weight 208.10
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Formula C7H14BrNO
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Color Off-white to yellow
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SMILES
C#CC[N+](C)(CCO)C.[Br-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (2)
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Journal Impact Factor
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Most Recent
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Adv Sci (Weinh)
Enzalutamide-Resistant STEAP4+ MyoCAF Secrete Phosphatidylcholine to Foster Progression by Activating Stemness in Hormone-Sensitive Prostate Cancer. [Abstract]2025 Sep 8:e10602. PMID: 40917018 -
Solvent & Solubility
DMSO : 125 mg/mL (600.67 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : 100 mg/mL (480.54 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO | 1 mM | 4.8054 mL | 24.0269 mL | 48.0538 mL | 120.1345 mL |
| 5 mM | 0.9611 mL | 4.8054 mL | 9.6108 mL | 24.0269 mL | |
| 10 mM | 0.4805 mL | 2.4027 mL | 4.8054 mL | 12.0135 mL | |
| 15 mM | 0.3204 mL | 1.6018 mL | 3.2036 mL | 8.0090 mL | |
| 20 mM | 0.2403 mL | 1.2013 mL | 2.4027 mL | 6.0067 mL | |
| 25 mM | 0.1922 mL | 0.9611 mL | 1.9222 mL | 4.8054 mL | |
| 30 mM | 0.1602 mL | 0.8009 mL | 1.6018 mL | 4.0045 mL | |
| 40 mM | 0.1201 mL | 0.6007 mL | 1.2013 mL | 3.0034 mL | |
| 50 mM | 0.0961 mL | 0.4805 mL | 0.9611 mL | 2.4027 mL | |
| 60 mM | 0.0801 mL | 0.4004 mL | 0.8009 mL | 2.0022 mL | |
| 80 mM | 0.0601 mL | 0.3003 mL | 0.6007 mL | 1.5017 mL | |
| 100 mM | 0.0481 mL | 0.2403 mL | 0.4805 mL | 1.2013 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Propargylcholine bromide Related Classifications
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