PROTAC BCL6 Degrader-3
Based on 1 Customer Validation
PROTAC BCL6 Degrader-3 (compound 92) is a BCL6 PROTAC degrader. PROTAC BCL6 Degrader-3 can be used for the study of cancer or an autoimmune disease.
(Pink: BCL6 ligand (HY-186068); Blue: Cereblon ligand (HY-W593794); Black: linker (HY-W267161)).
For research use only. We do not sell to patients.
- Purity: 99.76%
- CAS No.: 3005272-58-9
- Formula: C32H33ClFN9O3
- Molecular Weight:646.11
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All PROTACs Isoforms
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Biological Activity
Chemical Information
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CAS No. 3005272-58-9
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Appearance Solid
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Molecular Weight 646.11
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Formula C32H33ClFN9O3
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Color White to off-white
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SMILES
CN1C2=CC(N[C@H]3[C@@H](CN(C4=NC=C(Cl)C(NC5=C(F)C=C(N(C(C6)=O)C)C6=C5)=N4)CC3)C)=CC=C2C(C7C(NC(CC7)=O)=O)=N1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (154.77 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.5477 mL | 7.7386 mL | 15.4772 mL | 38.6931 mL |
| 5 mM | 0.3095 mL | 1.5477 mL | 3.0954 mL | 7.7386 mL | |
| 10 mM | 0.1548 mL | 0.7739 mL | 1.5477 mL | 3.8693 mL | |
| 15 mM | 0.1032 mL | 0.5159 mL | 1.0318 mL | 2.5795 mL | |
| 20 mM | 0.0774 mL | 0.3869 mL | 0.7739 mL | 1.9347 mL | |
| 25 mM | 0.0619 mL | 0.3095 mL | 0.6191 mL | 1.5477 mL | |
| 30 mM | 0.0516 mL | 0.2580 mL | 0.5159 mL | 1.2898 mL | |
| 40 mM | 0.0387 mL | 0.1935 mL | 0.3869 mL | 0.9673 mL | |
| 50 mM | 0.0310 mL | 0.1548 mL | 0.3095 mL | 0.7739 mL | |
| 60 mM | 0.0258 mL | 0.1290 mL | 0.2580 mL | 0.6449 mL | |
| 80 mM | 0.0193 mL | 0.0967 mL | 0.1935 mL | 0.4837 mL | |
| 100 mM | 0.0155 mL | 0.0774 mL | 0.1548 mL | 0.3869 mL |