PROTAC SMARCA2 degrader-17
PROTAC SMARCA2 degrader-17 (compound I-290) is a PROTAC degrader targeting SMARCA2; it degrades SMARCA2 proteins in A549 cells with an DC50 <100 nM, and a maximum degradation rate (Dmax%) >90 after 24 h of treatment.
For research use only. We do not sell to patients.
- CAS No.: 2568276-43-5
- Formula: C44H51N11O4
- Molecular Weight:797.95
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All PROTACs Isoforms
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Biological Activity
SMARCA2[1]
Chemical Information
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CAS No. 2568276-43-5
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Molecular Weight 797.95
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Formula C44H51N11O4
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SMILES
OC1=CC=CC=C1C2=CC(N3CC4CCC(N4C5=NC=C(C6CCN(C7CCC(C8=CC(N(C)C(N9C%10CCC(NC%10=O)=O)=O)=C9C=C8)CC7)CC6)C=N5)C3)=C(N)N=N2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)