Integrin alpha 8 beta 1
Integrin alpha 8 beta 1 is the most restricted beta-1 receptor, expressed chiefly on neurons, on mesenchymal cells of developing organs and in hair follicle dermal papillae. Its alpha-8 subunit recognizes RGD motifs in fibronectin, vitronectin, tenascin and latent TGF-beta-1, linking cells to specialized matrices during embryogenesis. In the nervous system it guides neurite outgrowth and cranial ganglion formation, and in the kidney it contributes to nephrogenesis. Alpha 8 beta 1 also participates in activating latent TGF-beta-1, placing it alongside alpha V beta 6 and alpha V beta 8 in TGF-beta biology. Because of its involvement in hair cycling and tissue remodeling, it is explored in dermatology and regenerative medicine research.
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Integrin alpha 8 beta 1 Recombinant Proteins (2)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
