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Cat. No.: HY-N13355

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Przewaquinone B

Name: Przewaquinone B
Brand: MedChemExpress
SKU: HY-N13355
Price: 600.00 USD
Availability: InStock
Rating: 5 (1 reviews)

Przewaquinone B is an abietane-type diterpene quinone (tanshinone) and a diterpenoid compound. Przewaquinone B can be isolated from the rhizomes of Salvia miltiorrhiza Bunge, the roots of Salvia przewarskii, and the roots of Salvia constanea. Przewaquinone B exhibits antitumor activity against cervical cancer and promyelocytic leukemia. Przewaquinone B can be used in research related to cervical cancer and promyelocytic leukemia.

For research use only. We do not sell to patients.

CAS No.: 76829-01-1
Formula: C₁₈H₁₂O₄
Molecular Weight:292.29

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Przewaquinone B Chemical Structure

CAS No.: 76829-01-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
- In Vitro
Chemical Information
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Biological Activity

Description

Cellular Effect

Cell Line	Type	Value	Description	References
HeLa	IC50	19.0 μM	Cytotoxicity against human cervical cancer HeLa cells. Cytotoxicity against human cervical cancer HeLa cells.	27032190
HL-60	IC50	3.0 μM	Cytotoxicity against human promyelocytic leukemia HL-60 cells. Cytotoxicity against human promyelocytic leukemia HL-60 cells.	27032190

In Vitro

Przewaquinone B exhibits weak cytotoxicity against HeLa cells (IC₅₀ = 19.0 μM) and significant cytotoxicity against HL-60 cells (IC₅₀ = 3.0 μM)^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 76829-01-1
Molecular Weight 292.29
Formula C₁₈H₁₂O₄
SMILES

O=C1C(C2=C(C3=C1C(C=CC=C4C)=C4C=C3)OC=C2CO)=O
Structure Classification
- Terpenoids
- Diterpenoids
Initial Source
- Plants
- Labiatae
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Wang X, et al. New developments in the chemistry and biology of the bioactive constituents of Tanshen. Med Res Rev. 2007 Jan;27(1):133-48. [Content Brief]

[2]. Tsukada H, et al. Two New Diterpenoids from Salvia przewarskii. Natural product communications. 2016 Feb;11(2):159-61. [Content Brief]

[3]. YANG M H, et al. Diterpenoids from Salvia species[J]. Pharmacy and Pharmacology Communications, 1996, 2(1): 69-71.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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