Phenylpropenamide derivatives as inhibitors of hepatitis B virus replication
- Bioorg Med Chem Lett. 2000 Dec 4;10(23):2687-90. doi: 10.1016/s0960-894x(00)00544-8.
Affiliations
- 1. Avid Therapeutics, Inc., Philadelphia, PA 19104, USA. [email protected]
PMID: 11128652
DOI: 10.1016/s0960-894x(00)00544-8
Abstract
A non-nucleoside class of compounds that inhibits the replication of hepatitis B virus (HBV) in Cell Culture has been discovered. A series of substituted analogues of phenylpropenamide 6 has been prepared and evaluated in the HepAD38 cellular assay. Structure-activity relationships of this series are discussed.
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