Phomoxanthones A and B, novel xanthone dimers from the endophytic fungus Phomopsis species

  • J Nat Prod. 2001 Aug;64(8):1015-8. doi: 10.1021/np010006h.
M Isaka  1 ,  A Jaturapat ,  K Rukseree ,  K Danwisetkanjana ,  M Tanticharoen ,  Y Thebtaranonth
Affiliations
  • 1. National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency, Rama 6 Road, Bangkok 10400, Thailand. [email protected]
PMID: 11520217 DOI: 10.1021/np010006h
Abstract

Phomoxanthones A (1) and B (2), two novel xanthone dimers, were isolated from the endophytic fungus Phomopsis sp. BCC 1323. Structures of 1 and 2 were elucidated by spectroscopic methods. These compounds exhibited significant in vitro antimalarial and antitubercular activities and cytotoxicity.

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