New and bioactive compounds from Streptomyces strains residing in the wood of Celastraceae

  • Planta. 2002 Nov;216(1):162-7. doi: 10.1007/s00425-002-0874-6.
Christian Pullen  1 ,  Petra Schmitz ,  Kristina Meurer ,  Daniel D v Bamberg ,  Stephanie Lohmann ,  Suzelei De Castro França ,  Ingrid Groth ,  Brigitte Schlegel ,  Ute Möllmann ,  Friedrich Gollmick ,  Udo Gräfe ,  Eckhard Leistner
Affiliations
  • 1. Institut für Pharmazeutische Biologie der Universität Bonn, Nussallee 6, 53115 Bonn, Germany.
PMID: 12430026 DOI: 10.1007/s00425-002-0874-6
Abstract

Wood from three different Plants of the Celastraceae growing in their natural habitats in Brazil (Maytenus aquifolia Mart.) and South Africa [Putterlickia retrospinosa van Wyk and Mostert, P. verrucosa (E. Meyer ex Sonder) Szyszyl.] was established as a source of endophytic bacteria using a medium selective for actinomycetes. Two isolates were identified as Streptomyces setonii and S. sampsonii whereas two Others were not assignable to any of the known Streptomyces species. They were preliminarily named Streptomyces Q21 and Streptomyces MaB-QuH-8. The latter strain produces a new chloropyrrol and chlorinated anthracyclinone. The chloropyrrol showed high activity against a series of multiresistent bacteria and mycobacteria.

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