The vasorelaxant activity of marrubenol and marrubiin from Marrubium vulgare

  • Planta Med. 2003 Jan;69(1):75-7. doi: 10.1055/s-2003-37042.
Sanae El Bardai ,  Nicole Morel ,  Maurice Wibo ,  Nicolas Fabre ,  Gabriel Llabres ,  Badiaa Lyoussi ,  Joëlle Quetin-Leclercq
PMID: 12567286 DOI: 10.1055/s-2003-37042
Abstract

Crude extracts of the aerial parts of Marrubium vulgare show a potent in vitro inhibition of KCl-induced contraction of rat aorta. Bio-guided fractionations, spectroscopic analysis and chemical derivatization revealed the furanic labdane diterpenes marrubenol and marrubiin as the most active compounds.

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