Progress in the studies on rutaecarpine

  • Molecules. 2008 Feb 6;13(2):272-300. doi: 10.3390/molecules13020272.
Seung Ho Lee  1 ,  Jong-Keun Son ,  Byeong Seon Jeong ,  Tae-Cheon Jeong ,  Hyeon Wook Chang ,  Eung-Seok Lee ,  Yurngdong Jahng
Affiliations
  • 1. College of Pharmacy, Yeungnam University, Gyeongsan 712-749 Korea.
PMID: 18305418 DOI: 10.3390/molecules13020272
Abstract

Rutaecarpine is an indolopyridoquinazolinone alkaloid isolated from Evodia rutaecarpa and related herbs, which has shown a variety of intriguing biological properties such as anti-thrombotic, Anticancer, anti-inflammatory and analgesic, anti-obesity and thermoregulatory, vasorelaxing activity, as well as effects on the cardiovascular and endocrine systems. Recent progress in the studies on the isolation, synthesis, structure-activity relationship studies, biological activities and metabolism of rutaecarpine are reviewed.

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