Lignans from the roots of Saururus chinensis

  • J Nat Prod. 2008 Oct;71(10):1771-4. doi: 10.1021/np8002723.
Chang-Seob Seo  1 ,  Ming-Shan Zheng ,  Mi-Hee Woo ,  Chong-Soon Lee ,  Sung-Ho Lee ,  Byeong-Seon Jeong ,  Hyeun-Wook Chang ,  Yurngdong Jahng ,  Eung-Seok Lee ,  Jong-Keun Son
Affiliations
  • 1. College of Pharmacy, Yeungnam University, 214-1 Dae-dong, Gyeongsan, Korea.
PMID: 18841903 DOI: 10.1021/np8002723
Abstract

Four new Lignans, saucerneol F (1), saucerneol G (2), saucerneol H (3), and saucerneol I (4), were isolated from the EtOAc Extract of the roots of Saururus chinensis, together with one known compound, saucerneol D (5). The structures of compounds 1-4 were elucidated by spectroscopic analysis. These compounds showed cytotoxic activities against HT-29, MCF-7, and HepG-2 cell lines.