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Enzymology of purine and pyrimidine antimetabolites used in the treatment of cancer

Chem Rev. 2009 Jul;109(7):2880-93. doi: 10.1021/cr900028p.

William B Parker ¹

Affiliations

PMID: 19476376 DOI: 10.1021/cr900028p

Products

Cat. No.

Product Name

Description

Target

Research Area
HY-A0004

Decitabine

99.97%, DNMT Inhibitor

target: DNA Methyltransferase; Apoptosis; Nucleoside Antimetabolite/Analog

Research Areas: Inflammation/Immunology; Infection; Cancer
HY-A0004R

Decitabine (Standard)

99.91%, DNMT Inhibitor

target: Reference Standards; DNA Methyltransferase; Apoptosis; Nucleoside Antimetabolite/Analog

Research Areas: Cancer
HY-A0004S

Decitabine-¹³C₅

Stable Isotope

target: Nucleoside Antimetabolite/Analog; DNA Methyltransferase; Apoptosis; Isotope-Labeled Compounds

Research Areas: Cancer
HY-A0004B

Decitabine methanesulfonate

DNMT Inhibitor

target: DNA Methyltransferase; Apoptosis; Nucleoside Antimetabolite/Analog

Research Areas: Cancer