Three new megastigmanes from the leaves of Annona muricata

  • J Nat Med. 2012 Apr;66(2):284-91. doi: 10.1007/s11418-011-0583-1.
Ayano Matsushige  1 ,  Katsuyoshi Matsunami ,  Yaichiro Kotake ,  Hideaki Otsuka ,  Shigeru Ohta
Affiliations
  • 1. Department of Xenobiotic Metabolism and Molecular Toxicology, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, Japan.
PMID: 21892756 DOI: 10.1007/s11418-011-0583-1
Abstract

Three new megastigmanes (1-3), named annoionols A and B (1, 2) and annoionoside (3), were isolated from the leaves of Annona muricata L. (Annonaceae) together with 14 known compounds (4-17). Among the known compounds, annoionol C (4) was isolated from a natural source for the first time. The structures of all compounds were elucidated by spectroscopic and chemical analyses.

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