ML345, A Small-Molecule Inhibitor of the Insulin-Degrading Enzyme (IDE)

TD Bannister  1 ,  H Wang  1 ,  SO Abdul-Hay  2 ,  A Masson  2 ,  F Madoux  3 ,  J Ferguson  3 ,  BA Mercer  3 ,  S Schurer  4 ,  A Zuhl  5 ,  BF Cravatt  5 ,  MA Leissring  2 ,  P Hodder  3
Affiliations
  • 1. Scripps Research Institute Department of Chemistry, Translational Research Institute, Jupiter, Florida 33458
  • 2. Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224
  • 3. Scripps Research Institute Molecular Screening Center, Lead Identification Division, Translational Research Institute, Jupiter, Florida 33458
  • 4. University of Miami, Miller School of Medicine, Miami FL 33136.
  • 5. Department of Chemical Physiology, TSRI, La Jolla, CA 92037
PMID: 23833801
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