The Pseudomonas Quinolone Signal (PQS): Not Just for Quorum Sensing Anymore

  • Front Cell Infect Microbiol. 2018 Jul 4:8:230. doi: 10.3389/fcimb.2018.00230.
Jinshui Lin  1  2 ,  Juanli Cheng  1  2 ,  Yao Wang  3  4 ,  Xihui Shen  3  4
Affiliations
  • 1. Shaanxi Engineering and Technological Research Center for Conservation and Utilization of Regional Biological Resources, Yan'an University, Yan'an, China.
  • 2. College of Life Sciences, Yan'an University, Yan'an, China.
  • 3. Shaanxi Key Laboratory of Agricultural and Environmental Microbiology, College of Life Sciences, Northwest A&F University, Yangling, China.
  • 4. State Key Laboratory of Crop Stress Biology for Arid Areas, Northwest A&F University, Yangling, China.
PMID: 30023354 DOI: 10.3389/fcimb.2018.00230
Abstract

The Pseudomonas Quinolone signal (PQS) has been studied primarily in the context of its role as a quorum-sensing signaling molecule. Recent data suggest, however, that this molecule may also function to mediate iron acquisition, cytotoxicity, outer-membrane vesicle biogenesis, or to exert host immune modulatory activities.

Keywords
PQS; Pseudomonas aeruginosa; cytotoxicity; immune regulation; iron acquisition; outer-membrane vesicles; quorum sensing.
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