Anti-human CD117 antibody-mediated bone marrow niche clearance in nonhuman primates and humanized NSG mice

  • Blood. 2019 May 9;133(19):2104-2108. doi: 10.1182/blood-2018-06-853879.
Hye-Sook Kwon  1 ,  Aaron C Logan  2 ,  Akanksha Chhabra  1 ,  Wendy W Pang  1 ,  Agnieszka Czechowicz  3  4  5 ,  Keri Tate  6 ,  Alan Le  1 ,  Jessica Poyser  1 ,  Roger Hollis  7 ,  Benjamin V Kelly  8 ,  Donald B Kohn  7  9 ,  Irving L Weissman  4  10  11  12 ,  Susan S Prohaska  1 ,  Judith A Shizuru  1  3  10  12
Affiliations
  • 1. Division of Blood and Marrow Transplantation, Department of Medicine, School of Medicine, Stanford University, Stanford, CA.
  • 2. Division of Malignant Hematology and Blood and Marrow Transplantation, Department of Medicine, University of California, San Francisco, San Francisco, CA.
  • 3. Division of Stem Cell Transplantation and Regenerative Medicine, Department of Pediatrics.
  • 4. Department of Pathology, and.
  • 5. Department of Developmental Biology, School of Medicine, Stanford University, Stanford, CA.
  • 6. Stanford Laboratory for Cell and Gene Medicine, Stanford University, Palo Alto, CA.
  • 7. Department of Microbiology, Immunology, and Molecular Genetics.
  • 8. Department of Orthopaedic Surgery, David Geffen School of Medicine, and.
  • 9. Division of Hematology/Oncology, Department of Pediatrics, University of California, Los Angeles, Los Angeles, CA; and.
  • 10. Stanford Cancer Institute.
  • 11. Ludwig Center for Cancer Stem Cell Research and Medicine, and.
  • 12. Institute for Stem Cell Biology and Regenerative Medicine, School of Medicine, Stanford University, Stanford, CA.
PMID: 30617195 DOI: 10.1182/blood-2018-06-853879
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